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Updated: May 10, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
13:58

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Published on: October 22, 2012

HLA peptide length preferences control CD8+ T cell responses

Melissa J Rist1, Alex Theodossis, Nathan P Croft

  • 1Centre for Immunotherapy and Vaccine Development, Queensland Institute of Medical Research, Brisbane, Queensland 4029, Australia.

Journal of Immunology (Baltimore, Md. : 1950)
|June 11, 2013
PubMed
Summary

Human leukocyte antigen (HLA) polymorphism influences T cell responses by altering peptide length preferences. Different HLA-B variants bind and present varying peptide lengths, diversifying immune recognition of viral antigens like EBV

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