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Updated: May 10, 2026

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Published on: December 22, 2023

Lung function after preterm birth: development from mid-childhood to adulthood.

Maria Vollsæter¹, Ola Drange Røksund, Geir Egil Eide

¹Department of Clinical Science, Section for Pediatrics, University of Bergen, Bergen, Norway. maria.vollsaeter@helse-bergen.no

|June 11, 2013

Summary

This summary is machine-generated.

Extreme preterm birth, especially with neonatal bronchopulmonary dysplasia, leads to lasting airway obstruction into adulthood. Lung function tracks similarly across groups, but at lower levels for preterm infants.

Keywords:

COPD epidemiology Clinical Epidemiology Paediatric Lung Disaese

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Last Updated: May 10, 2026

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

Published on: December 22, 2023

Area of Science:

Pulmonology
Neonatology
Pediatric Medicine

Background:

Advances in perinatal care increase survival rates for extremely preterm infants.
Concerns exist regarding the long-term pulmonary health consequences of preterm birth and its treatments.
Preterm birth may contribute to chronic airway obstruction in adulthood.

Purpose of the Study:

To evaluate the longitudinal development of spirometric lung function from mid-childhood to adulthood in individuals born extremely preterm.
To compare lung function trajectories between preterm-born and term-born individuals.

Main Methods:

Two population-based cohorts of infants born at gestational age ≤28 weeks or birth weight ≤1000 g underwent lung function testing.
Tests were conducted at ages 10 and 18, and 18 and 25 years, with matched term-born controls.
Longitudinal development was analyzed, stratified by the presence and severity of neonatal bronchopulmonary dysplasia (BPD).

Main Results:

Preterm infants, particularly those with neonatal BPD, exhibited significantly lower forced expiratory volume in 1 second and mid-expiratory flow compared to term-born controls.
These differences persisted across all assessment points.
Lung function indices showed similar tracking patterns within preterm and term-born groups, irrespective of BPD severity.

Conclusions:

Airway obstruction is a persistent condition from mid-childhood through adulthood following extreme preterm birth, most pronounced in those with neonatal BPD.
Despite lower absolute values, lung function development trajectories were comparable between preterm and term-born individuals.