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Pachychoroid pigment epitheliopathy
David J Warrow1, Quan V Hoang, K Bailey Freund
1Department of Ophthalmology, The New York Eye and Ear Infirmary, New York, NY, USA.
Pachychoroid pigment epitheliopathy, characterized by thickened choroids and retinal pigment epithelial changes, is often misdiagnosed. Early recognition aids in accurate diagnosis and avoids unnecessary treatments.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Choroidal Disorders
Background:
- Pachychoroid pigment epitheliopathy is a distinct clinical entity within the spectrum of pachychoroid diseases.
- It is often misdiagnosed as age-related macular degeneration or inflammatory chorioretinitis.
Observation:
- A case series of nine patients diagnosed with pachychoroid pigment epitheliopathy was analyzed.
- Patients underwent comprehensive ophthalmic examinations, including fundus photography, autofluorescence, and enhanced depth imaging optical coherence tomography (EDI-OCT).
Findings:
- Pachychoroid pigment epitheliopathy presents with reduced fundus tessellation, retinal pigment epithelial changes, and increased subfoveal choroidal thickness (mean 460.2 μm) on EDI-OCT.
- No patients developed subretinal fluid, differentiating it from other pachychoroid conditions.
Implications:
- Accurate diagnosis of pachychoroid pigment epitheliopathy is crucial to avoid unnecessary interventions.
- Enhanced depth imaging optical coherence tomography is vital for confirming the diagnosis by visualizing choroidal thickening and retinal pigment epithelial abnormalities.
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