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Updated: May 10, 2026

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Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
N-Triethylene glycol (N-TEG) as a surrogate for the N-methyl group: application to Sansalvamide A peptide analogs
Ana I Fernández-Llamazares1, Jesús García, Vanessa Soto-Cerrato
1Institute for Research in Biomedicine (IRB), Barcelona Science Park (PCB), Baldiri Reixac 10, 08028 Barcelona, Spain.
Abstract:
Here we studied the N-triethylene glycol (N-TEG) group as a surrogate for the N-Me group in Sansalvamide A peptide. The five N-TEG and N-Me analogs of this cyclic pentapeptide were synthesized, and their biological activity, lipophilicity and conformational features were compared.

