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Updated: May 10, 2026

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
Heavily thickened pericardium with constrictive pericarditis
Abid Hussain Laghari1, Javed Majid Tai
1Section of Cardiology, Department of Medicine, Aga Khan University Hospital, Karachi.
Constrictive pericarditis, a heart condition causing fluid buildup, can be effectively treated with pericardiectomy. This surgical procedure removes the inflamed pericardium, relieving symptoms and restoring normal heart function.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Constrictive pericarditis is a serious condition characterized by impaired diastolic filling of the heart due to pericardial thickening and restriction.
- Symptoms include dyspnea, edema, and elevated jugular venous pressure, often mimicking heart failure.
Observation:
- A middle-aged male presented with exertional dyspnea and leg swelling.
- Clinical examination revealed signs of fluid overload including elevated JVP, pedal edema, pleural effusions, and hepatomegaly.
- Cardiac imaging, including echocardiography and CT, confirmed heavily thickened pericardium indicative of constrictive pericarditis.
Findings:
- Echocardiography demonstrated significant pericardial thickening and diastolic dysfunction consistent with constriction.
- Cardiac CT provided detailed anatomical information of the thickened pericardium.
- Surgical pericardiectomy was performed to relieve the pericardial restriction.
Implications:
- Pericardiectomy successfully reversed the echocardiographic features of constriction.
- The patient experienced complete symptom resolution and became asymptomatic post-surgery.
- This case highlights the efficacy of pericardiectomy in managing symptomatic constrictive pericarditis.
Related Concept Videos
Pericarditis I: Introduction
Pericarditis III: Medical Management
Pericarditis II: Clinical Features and Diagnostic Tests
Cardiomyopathy IV: Restrictive Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Rheumatic Heart Disease I: Introduction

