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Updated: May 10, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
Answering human papillomavirus vaccine concerns; a matter of science and time
David Hawkes1, Candice E Lea, Matthew J Berryman
1The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Victoria 3010, Australia. david.hawkes@florey.edu.au.
Abstract:
Since the introduction of the HPV vaccine, questions have been asked about its efficacy in preventing cancer linked with HPV. Concerns about the HPV vaccine safety profile have also been raised. This paper highlights the rapidly growing body of evidence (including clinical trials and post-marketing surveillance) illustrating both the safety of the HPV vaccine, through a detailed investigation of reported adverse events, and its efficacy in reducing both HPV infections rates and the resulting drop in cervical lesions, which have been demonstrated to be good predictors of cervical cancer risk.
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