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Updated: May 10, 2026

Production and Targeting of Monovalent Quantum Dots
Published on: October 23, 2014
Site-specific cellular delivery of quantum dots with chemoselectively-assembled modular peptides
James B Delehanty1, Juan B Blanco-Canosa, Christopher E Bradburne
1Center for Bio/Molecular Science and Engineering, Code 6900, USA. James.delehanty@nrl.navy.mil
Abstract:
Modular peptides displaying both quantum dot bioconjugation motifs and specific subcellular targeting domains were constructed using a chemoselective aniline-catalyzed hydrazone coupling chemistry. Peptides were ratiometrically assembled onto quantum dots to facilitate their specific delivery to either the plasma membrane, endosomes, the cytosol or the mitochondria of target cells.
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