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Updated: May 10, 2026
A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse
Published on: November 17, 2016
[Short-term and long-term complications after transplantation of cultivated limbal epithelium]
D Meller1, H Thomasen, M-S Hanet
1Klinik für Erkrankungen des vorderen Augenabschnitts, Zentrum für Augenheilkunde, Universität Duisburg-Essen, Hufelandstr. 55, 45122, Essen, Deutschland. daniel.meller@uk-essen.de
Abstract:
Recent advances in tissue engineering have facilitated the development of new strategies in ocular surface reconstruction. Limitations and possibilities of ex vivo cultivation and limbal epithelium cell culture techniques as well as the short and long-term complications after transplantation of ex vivo expansion of cultivated limbal epithelium for the treatment of limbal stem cell deficiency are summarized in this review.
