Related Experiment Video
Updated: May 10, 2026

06:09
Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
Published on: June 7, 2019
Combining checkpoint inhibitors and BRAF-targeted agents against metastatic melanoma
Zachary A Cooper1, Dennie T Frederick, Zain Ahmed
1Division of Surgical Oncology; Massachusetts General Hospital; Boston MA USA.
Oncoimmunology
|June 14, 2013
Abstract:
The combination of BRAF-targeted agents with immune checkpoint inhibitors represents a recent advance in the treatment of melanoma, even though each of these therapeutic approaches alone has specific limitations. Increasing evidence suggests indeed the existence of a synergistic interaction between these therapeutic modalities.
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