[Use of vitamins A and E for correction of the immune response to effects of vibration]

A sharp decline in the development of humoral immune response to sheep's erythrocytes was identified in rats after vibrational effect. Retinol acetate (RA) and tocopherol acetate (TA) injections markedly increased its development. In rats affected with vibration, after RA injections the spleen adhesive cells incubate (SACI) suppresses humoral immune response development, and the spleen non-adhesive cell incubate (SNCI) stimulates it considerably. In TA-injected rats, both SACI and SNCI do not influence the development of humoral immune response. The splenocytes of intact rats, treated with TA-injected rats' muscle incubate, do not exert immunosuppressive factors, as contrary to the splenocytes treated with RA-injected rats' muscle incubate.