Related Experiment Video

Updated: May 10, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

Speckle tracking echocardiography-determined measures of global and regional left ventricular function correlate with

John W Petersen1, Talha F Nazir, Licheng Lee

  • 1Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida, USA. john.petersen@medicine.ufl.edu

Cardiovascular Ultrasound
|June 15, 2013
PubMed

Insights

Speckle tracking echocardiography (STE) measures of heart muscle function correlate with patient exercise capacity. These strain measures, particularly longitudinal strain, offer a better assessment of heart failure, especially in preserved ejection fraction cases.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Standard heart function tests often miss left ventricular dysfunction in heart failure patients.
  • These standard measures do not correlate with patient functional capacity.

Purpose of the Study:

  • To assess if speckle tracking echocardiography (STE) measures of myocardial contractility correlate with functional capacity.
  • To evaluate this association in patients with and without preserved ejection fraction.

Main Methods:

  • 68 adult patients' functional status was assessed using the Duke Activity Status Index (DASI).
  • Left ventricular ejection fraction was measured using Simpson's biplane method.
  • QLAB software quantified peak strain measures.

Main Results:

  • Global and regional strain measures (longitudinal, circumferential, radial) showed a strong linear association with DASI scores.
  • Inferolateral segment longitudinal strain had the highest correlation with DASI (r = -0.72).
  • In patients with ejection fraction ≥45%, STE longitudinal strain correlated significantly with DASI, unlike ejection fraction or E/e'.

Conclusions:

  • STE-derived measures of left ventricular function strongly correlate with functional capacity across ejection fraction ranges.
  • STE strain measures, especially longitudinal strain, are valuable for diagnosing left ventricular inadequacy in heart failure, particularly with preserved ejection fraction.
Abstract

More Related Videos

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

Related Concept Videos

Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...