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Published on: November 23, 2012
Draft Genome Sequence of Streptococcus agalactiae PR06.
Irma Syakina Mz1, L K Teh, M Z Salleh
1Pharmacogenomics Centre (PROMISE), Faculty of Pharmacy, Universiti Teknologi MARA Malaysia, Puncak Alam Campus, Selangor Darul Ehsan, Malaysia.
Genome Announcements
|June 15, 2013
Summary
Streptococcus agalactiae, also known as group B Streptococcus (GBS), is a bacterium causing bovine mastitis and human diseases. This study presents the genome sequence of a GBS strain from a septicemic patient in Malaysia.
Area of Science:
- Microbiology
- Genomics
- Bacterial Pathogenesis
Background:
- Streptococcus agalactiae (group B Streptococcus, GBS) is a Gram-positive bacterium.
- Initially identified as a cause of bovine mastitis.
- GBS has emerged as a significant human pathogen.
Purpose of the Study:
- To report the draft genome sequence of Streptococcus agalactiae PR06.
- To analyze the genome of a GBS strain isolated from a septicemic patient.
Main Methods:
- Bacterial isolation from a septicemic patient.
- Whole-genome sequencing.
- Bioinformatic analysis of the draft genome.
Main Results:
- The draft genome sequence of S. agalactiae PR06 was successfully generated.
- The isolate was obtained from a septicemic patient in Malaysia.
- This provides genomic data for a clinically relevant GBS strain.
Conclusions:
- The availability of the S. agalactiae PR06 genome sequence aids in understanding GBS pathogenesis.
- Genomic data can inform future research on GBS epidemiology and treatment.
- This study contributes to the genomic resources for Streptococcus agalactiae.
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