Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 10, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
07:06

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

Published on: November 15, 2017

3D-printed devices for continuous-flow organic chemistry.

Vincenza Dragone1, Victor Sans, Mali H Rosnes

  • 1School of Chemistry, University of Glasgow, University Avenue, Glasgow G12 8QQ, UK. Web: http://www.croninlab.com.

Beilstein Journal of Organic Chemistry
|June 15, 2013
PubMed
Summary

This study combines 3D-printing and flow chemistry for organic synthesis. Researchers created custom flow systems with 3D-printed reactors and real-time analysis, demonstrating versatile product formation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mapping Evolution of Molecules across Biochemistry with Assembly Theory.

Journal of chemical information and modeling·2026
Same author

Dimensional Evolution from a Giant Molybdenum-Red Cage-like {Mo<sub>200</sub>} to 1D Chains Enabling Ultrahigh Proton Conduction.

Journal of the American Chemical Society·2026
Same author

3D-Printed Platforms for Enzyme Immobilisation Screening and Direct Translation into Continuous-Flow Biocatalysis.

ChemSusChem·2026
Same author

Chemputer and chemputation-A universal chemical compound synthesis machine.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Verification and execution of the scientific literature via chemputation augmented by large language models.

Communications chemistry·2026
Same author

Spontaneous assemblies of gigantic polyoxomolybdates; from structure and properties to synthetic methods.

Dalton transactions (Cambridge, England : 2003)·2026

Area of Science:

  • Organic Chemistry
  • Chemical Engineering
  • Materials Science

Background:

  • Flow chemistry offers processing advantages for organic synthesis.
  • 3D-printing enables rapid prototyping of custom chemical hardware.

Purpose of the Study:

  • To combine 3D-printing with flow chemistry for versatile organic compound synthesis.
  • To demonstrate the creation of complex, custom flow systems using 3D-printed reactionware.

Main Methods:

  • Utilized 3D-printing to fabricate robust and inexpensive reactionware devices.
  • Connected 3D-printed reactors in series using standard fittings to create custom flow systems.
  • Integrated an Attenuated Total Reflectance-Infrared (ATR-IR) flow cell for in-line, real-time analysis.
Keywords:
3D printingflow IRflow chemistryimine reductionimine synthesisin-line analysismillifluidicsreactionware

More Related Videos

Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations
13:09

Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations

Published on: January 4, 2018

Related Experiment Videos

Last Updated: May 10, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
07:06

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

Published on: November 15, 2017

Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations
13:09

Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations

Published on: January 4, 2018

Main Results:

  • Successfully synthesized organic compounds using the integrated 3D-printed flow system.
  • Demonstrated the synthesis of imines and reduction of imines as proof-of-concept reactions.
  • Showcased how varying reactor configurations and substrates yield different products.

Conclusions:

  • 3D-printing and flow chemistry integration provides a versatile platform for organic synthesis.
  • Customizable 3D-printed flow systems facilitate complex reaction setups and real-time monitoring.
  • This approach enables efficient exploration of reaction parameters and product diversity.