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Cardiovascular risk factors in men with ischemic heart disease and erectile dysfunction
Yael Pauker-Sharon1, Yaron Arbel, Ariel Finkelstein
1Sackler School of Medicine, Tel-Aviv University, Israel.
Insights
Erectile dysfunction (ED) and cardiovascular risks are common in men with ischemic heart disease (IHD). Only age independently predicts significant ED in this group, highlighting the importance of age in cardiovascular health.
Area of Science:
- Cardiology
- Urology
- Men's Health
Background:
- Ischemic heart disease (IHD) and erectile dysfunction (ED) frequently coexist in aging men.
- Cardiovascular risk factors are common in men diagnosed with IHD.
Purpose of the Study:
- To determine the prevalence of cardiovascular risk factors in men with IHD and ED.
- To identify which cardiovascular risk factors are independently associated with ED in men with IHD.
Main Methods:
- A study involving 171 men undergoing coronary angiography.
- Assessment of cardiovascular risk factors including age, diabetes, hypertension, smoking, hyperlipidemia, and cardiac function.
- Utilized the Sexual Health Inventory for Males (SHIM) questionnaire to categorize ED severity.
- Employed binary regression analysis to establish independent associations between risk factors and ED.
Main Results:
- A high prevalence of ED was observed, with 35.7% experiencing mild ED and 46.8% experiencing significant ED.
- Over half of the participants (59.1%) presented with three or more cardiovascular risk factors.
- Age was the sole cardiovascular risk factor independently linked to significant ED (OR 1.154, P <.0001).
- No cardiovascular risk factors were found to be independently associated with mild ED.
Conclusions:
- Erectile dysfunction and associated cardiovascular risks are highly prevalent in men with IHD.
- Age is a significant independent predictor of significant ED in men with IHD.
- These findings underscore the intricate link between cardiovascular health and erectile function in this patient population.
Objective:
To study the prevalence of cardiovascular risk factors in men with ischemic heart disease (IHD) and erectile dysfunction (ED).
Methods:
We studied cardiovascular risk factors in men with IHD and ED, who undergo coronary angiography. All men filled the Sexual Health Inventory for Males questionnaire (SHIM). SHIM questionnaire scores between 17 and 21 represented mild ED. SHIM questionnaire scores of 16 or lower represented significant ED. Cardiovascular risk factors included the following: age, diabetes mellitus, hypertension, smoking, hyperlipidemia, left ventricular ejection fraction ≤30%, and 3-vessel disease. Binary regression analysis was used to study which cardiovascular risk factors were independently associated with ED.
Results:
The study included 171 men. Mean age was 64.2 ± 12.6 years. Overall, 61 men (35.7%) had mild ED and 80 men (46.8%) had significant ED. More than half of men (n = 101; 59.1%) had 3 or more cardiovascular risk factors. Age was the only cardiovascular risk factor independently associated with significant ED (odds ratio 1.154; 95% confidence interval 1.081-1.232; P <.0001). No cardiovascular risk factors were independently associated with mild ED.
Conclusion:
ED and its cardiovascular risk factors are highly prevalent in men with IHD. However, only age is independently associated with significant ED in this population.
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