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[Papular mycosis fungoides].
D Brajon1, N Bonnet, J-P Dales
1Service de dermatologie, hôpital Nord, chemin de Bourrely, 13009 Marseille, France. delphine.brajon@gmail.com
Annales De Dermatologie Et De Venereologie
|June 19, 2013
Summary
Papular mycosis fungoides (PMF) is a recently described variant of cutaneous T-cell lymphoma. This condition presents as a chronic, non-pruritic rash and appears to have a good prognosis with standard treatments.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma.
- A novel variant, papular mycosis fungoides (PMF), has been recently identified.
- This report details a case and reviews existing literature on PMF.
Observation:
- A 63-year-old male presented with erythematous, non-pruritic papular lesions on the trunk.
- Skin biopsy revealed moderately dense epidermotropic lymphocytic infiltration, consistent with MF.
- CD30 screening was negative, and treatment with potent corticosteroids showed significant efficacy.
Findings:
- Papular mycosis fungoides (PMF) is characterized by chronic, non-pruritic papular rash, distinct from classic MF lesions.
- Histopathology shows epidermotropic subepidermal infiltrate, predominantly CD4+ T-cells.
- The condition affects individuals aged 31-63, with no apparent gender predilection.
Implications:
- PMF is considered an incipient MF variant with a favorable prognosis.
- Effective treatment options include standard therapies for early-stage MF.
- Further research with larger patient cohorts is needed to fully characterize PMF and its long-term outcomes.
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