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Updated: May 10, 2026

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
[Acute disseminated encephalomyelitis (ADEM): its diagnostic criteria and therapy]
1Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University.
Abstract:
Acute disseminated encephalomyelitis (ADEM) is an immune-mediated central nervous system disorder in an individual with genetic susceptibility. It is characterized by acute or subacute onset of multifocal neurologic deficits with encephalopathy, often following a viral illness or vaccination. Since ADEM is diverse in its clinical features, the diagnostic criteria of ADEM require the exclusion of other etiologies. In this review, I will explain the diagnostic algorism and criteria, and therapy of ADEM.
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