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Updated: May 10, 2026

Separation of Aldehydes and Reactive Ketones from Mixtures Using a Bisulfite Extraction Protocol
Published on: April 2, 2018
Aldehydes and ketones form intermediate π complexes with the Gilman reagent, Me2CuLi, at low temperatures in
Steven H Bertz1, Richard A Hardin, Craig A Ogle
1Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, USA. sbertz1@uncc.edu
Abstract:
Typical aldehydes and ketones form π complexes with Me2CuLi at low temperatures in tetrahydrofuran. They range in stability from fleeting intermediates at -100 °C to entities that persist up to -20 °C. Three subsequent reaction pathways have been identified.
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