Examination of the effect of histodil prophylaxis in infarction patients with inhibited haemostasis

The initiation of anticoagulants and drugs with platelet aggregation inhibiting properties is justified for the treatment of myocardial infarction in a great number of conditions. The well-known complications of this therapy are gastro-intestinal haemorrhage and the concomitant discomfort. In the period from 1983 to 1986 Histodil was given as adjuvant to therapy for infarction patients with ulcer, gastro-intestinal haemorrhage, hyperacidity or other epigastric burn-pain syndrome in history. The patients treated at our department between 1979-82 had not received Histodil for this purpose. According to the retrospective examinations the preventive effect of Histodil prophylaxis was 100%. Therefore the drug may be recommended to myocardial infarction patients in whom the inhibition of haemostasis means an increased risk of gastro-intestinal alteration.