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Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Related Experiment Video

Updated: May 10, 2026

An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model

An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model

Published on: January 13, 2023

Tumor-targeted photodynamic therapy.

Naoto Shirasu¹, Sung Ouk Nam, Masahide Kuroki

¹Department of Biochemistry, Faculty of Medicine, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka, Japan. shirasu@fukuoka-u.ac.jp

Anticancer Research

|June 20, 2013

Summary

Photodynamic therapy (PDT) uses light-activated drugs to treat diseases like cancer. New tumor-targeting strategies improve PDT effectiveness by minimizing side effects on healthy tissues.

Keywords:

Drug delivery photodynamic therapy photosensitizer review tumor targeting

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Last Updated: May 10, 2026

An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model

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Published on: January 13, 2023

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro

Published on: March 18, 2014

Area of Science:

Oncology
Biomedical Engineering
Photochemistry

Background:

Photodynamic therapy (PDT) is a clinical treatment for cancer and other diseases.
PDT involves photosensitizers and light to induce cell death.
Current PDT methods face challenges with tumor selectivity and side effects.

Purpose of the Study:

To review current tumor-targeting strategies for photodynamic therapy.
To discuss the rationale behind developing targeted PDT approaches.
To highlight advancements in improving PDT efficacy and safety.

Main Methods:

Review of existing literature on tumor-targeted PDT.
Analysis of various photosensitizer delivery and targeting mechanisms.
Discussion of preclinical and clinical data on targeted PDT.

Main Results:

Targeted PDT approaches enhance photosensitizer accumulation in tumors.
Improved tumor selectivity reduces damage to surrounding healthy tissues.
Various strategies, including ligand-conjugation and nanoparticle delivery, show promise.

Conclusions:

Tumor-targeted PDT offers a promising strategy to improve treatment outcomes.
Overcoming limitations of traditional PDT requires innovative targeting methods.
Further research into targeted PDT is crucial for clinical translation.