[The use of a soy protein isolate in the diet therapy of patients with alimentary obesity]

Patients with alimentary obesity received a diet with 1/3 amount of protein substituted for soya protein isolate, daily, during 4 weeks. The influence of the dietotherapeutic course on protein, lipid metabolism, on bile acid and lipid composition of bile and on the immunologic state of the patients was studied. Blood and bile lipid content and the fraction of cholesterol esters were studied by thin-layer chromatography, lipid composition by disc electrophoresis in polyacrylamide gel, protein fractions by paper electrophoresis; the immunologic state was studied by the blast-transformation test and immunoglobulin assay. It has been established that this diet influences the parameters studied: the levels of total lipids, cholesterol, phospholipids, lipoproteins of low and very low density are decreased, the content of high density lipoproteins is increased, the level of globulin fractions is normalized, and the content of total protein is reduced to the normal, bile acid and lipid composition of bile and the immunologic state are improved.