[Breast diseases in patients with hyperandrogenism]

The study has been undertaken in 40 women with excessive androgen levels in the age range of 22 to 38 years. Various types of mastopathy were found in 34 and fatty degeneration of the glandular tissue in 6 women. On the basis of clinical and laboratory studies, the patients were assigned to 3 groups: ovarian hyperandrogenism, adrenal and ovarian-adrenal hyperandrogenism. Breast hyperplasia was seen in all groups, but adenofibrosis occurred in groups I and III at a 2-2.5-fold higher rate as compared with group II. The patients with hyperandrogenism, anovulation, increased body mass index, low hirsute number and polycystic ovaries were at the highest risk of dyshormonal mammary hyperplasia. An adequate therapeutic approach was suggested for mastopathies in hyperandrogenic patients.