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[Hypertensive pregnancy in diabetes--risk factors and influence on future life]
Daniel Gordin1, Per-Henrik Groop, Kari Teramo
1HYKS, nefrologian klinikka, ja Folkhälsanin tutkimuskeskus.
Pre-eclampsia and gestational hypertension are potentially dangerous entities causing maternal and fetal morbidity and mortality. Interestingly, the risk factors for these two conditions differ and it is thought that they also differ in their pathophysiological background. Notably, women with diabetes have an increased risk for de novo hypertension during pregnancy compared to non-diabetic subjects. However, among diabetic patients poor glycaemic control has been shown to increase the risk for pre-eclampsia. Furthermore, women with a history of pre-eclampsia suffer more often from cardiovascular disease later in life. New data regarding long-term effects of hypertensive pregnancies on late diabetic complications have been published that may be of clinical relevance in the prevention of these complications.
Pre-eclampsia and gestational hypertension are potentially dangerous entities causing maternal and fetal morbidity and mortality. Interestingly, the risk factors for these two conditions differ and it is thought that they also differ in their pathophysiological background. Notably, women with diabetes have an increased risk for de novo hypertension during pregnancy compared to non-diabetic subjects. However, among diabetic patients poor glycaemic control has been shown to increase the risk for pre-eclampsia. Furthermore, women with a history of pre-eclampsia suffer more often from cardiovascular disease later in life. New data regarding long-term effects of hypertensive pregnancies on late diabetic complications have been published that may be of clinical relevance in the prevention of these complications.
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