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Using Scaffold Liposomes to Reconstitute Lipid-proximal Protein-protein Interactions In Vitro
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Scaffolding proteins: not such innocent bystanders.

F Donelson Smith1, John D Scott

  • 1Howard Hughes Medical Institute, Department of Pharmacology, University of Washington, Seattle, WA 98195, USA. smithdon@uw.edu

Current Biology : CB
|June 22, 2013
PubMed
Summary

Protein kinase scaffolds, once thought inert, actively participate in signal relay. These organizational elements enhance cellular signal transduction by facilitating sequential enzyme information transfer.

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