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Related Experiment Video

Updated: May 10, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

[OCD: when limbic systems start looping...].

João Flores Alves dos Santos¹, Luc Mallet

¹Service de psychiatrie de liaison et d'intervention de crise, hôpitaux universitaires de Genève, 1211 Genève 14, Suisse.

La Revue Du Praticien

|June 25, 2013

Summary

This summary is machine-generated.

Deep brain stimulation (DBS) effectively reduces severe Obsessive Compulsive Disorder (OCD) symptoms and improves functioning in non-responsive patients. This case study highlights DBS

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Area of Science:

Neuroscience
Psychiatry
Neurosurgery

Background:

Obsessive Compulsive Disorder (OCD) affects 2-3% of the population, often with significant functional impairment.
Approximately 30% of OCD patients exhibit persistent symptoms despite standard pharmacological and psychotherapeutic interventions.
Refractory OCD poses a substantial challenge in clinical practice, necessitating advanced treatment modalities.

Observation:

A clinical case of severe, treatment-resistant Obsessive Compulsive Disorder (OCD) is presented.
Deep Brain Stimulation (DBS) targeting the subthalamic nucleus was employed as an advanced therapeutic option.
The patient's response to DBS was meticulously monitored to assess treatment efficacy.

Findings:

Deep Brain Stimulation (DBS) of the subthalamic nucleus resulted in significant reduction of Obsessive Compulsive Disorder (OCD) symptom severity.
The patient demonstrated marked improvement in overall functioning following DBS therapy.
Objective and subjective measures confirmed the positive impact of DBS on quality of life.

Implications:

Deep Brain Stimulation (DBS) represents a viable and effective treatment option for severe, refractory Obsessive Compulsive Disorder (OCD).
This case contributes to the growing body of evidence supporting DBS in psychiatric disorders.
Further research into DBS may elucidate the underlying pathophysiology of Obsessive Compulsive Disorder (OCD).