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Updated: May 10, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
[Management of hypertension recorded as at least 180/110 mmHg]
1Unité d'hypertension artérielle, clinique de cardiologie, CHU de Grenoble, 38043 Grenoble Cedex 09, France. jpbaguet@chu-grenoble.fr
Insights
Severe hypertension (Stage 3) requires prompt management. Treatment varies from outpatient oral medications for hypertensive urgency to intensive care for hypertensive emergencies, prioritizing safe blood pressure reduction.
Area of Science:
- Cardiology
- Nephrology
- Internal Medicine
Context:
- Stage 3 hypertension, or severe hypertension, is a common and serious condition.
- It can arise from poorly controlled chronic hypertension or present acutely, posing significant patient burden.
- Symptomatic severe hypertension affecting target organs necessitates rapid and appropriate medical intervention.
Purpose:
- To outline the distinct management strategies for hypertensive urgency versus hypertensive emergency.
- To emphasize the critical need for timely and tailored blood pressure reduction in severe hypertension.
Summary:
- Hypertensive urgency involves outpatient oral treatment, while hypertensive emergencies require hospitalization and intravenous antihypertensive therapy.
- The primary goal is to lower blood pressure progressively and safely, avoiding sudden drops.
- Clinical context dictates the speed and magnitude of blood pressure reduction.
Impact:
- Facilitates appropriate clinical decision-making for severe hypertension cases.
- Improves patient outcomes by ensuring timely and effective treatment.
- Highlights the importance of distinguishing between urgency and emergency for optimal care pathways.
Abstract:
Stage 3 hypertension (severe) is far from rare. It may be part of a previous hypertension condition which is difficult to control, or occur more acutely, in which case it will be harder for the patient to bear. When it is symptomatic and a fortiorione or more organs targeted by hypertension are affected, management must be fast and appropriate. It may take the form of a hypertensive urgency, in which case the investigations and treatment usually take place in outpatients, with oral treatment. it may also be a hypertensive emergency for which treatment involves hospitalization in an intensive care unit with intravenous anti-hypertensive treatment. A reduction in blood pressure must be obtained rapidly but not suddenly; it must be more or less significant depending on the clinical situation, and also progressive.
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