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Imaging-based diagnostic systems for hepatocellular carcinoma.

Irene Cruite1, An Tang, Claude B Sirlin

  • 1Department of Radiology, University of Washington Medical Center, Seattle, WA, USA.

AJR. American Journal of Roentgenology
|June 25, 2013
PubMed
Summary

Imaging systems aid in diagnosing liver cancer in at-risk patients. However, current systems have limitations and inconsistencies, hindering clinical integration and research. This review critically appraises these diagnostic systems and suggests future advancements.

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Area of Science:

  • Radiology
  • Hepatology
  • Oncology

Background:

  • Noninvasive imaging is crucial for managing patients with cirrhosis or hepatocellular carcinoma (HCC) risk factors.
  • International organizations have developed diagnostic systems for liver imaging in at-risk populations over the past 12 years.

Purpose of the Study:

  • To synthesize and critically appraise current imaging-based diagnostic systems for HCC.
  • To propose future directions for advancing noninvasive HCC diagnosis and staging.

Main Methods:

  • Literature review and critical appraisal of published imaging-based diagnostic systems.
  • Synthesis of systems endorsed by major scientific societies for HCC diagnosis and staging.

Main Results:

  • Multiple imaging-based diagnostic systems exist for HCC, representing significant advancements.
  • These systems exhibit limitations and inconsistencies, potentially impacting clinical practice and research.

Conclusions:

  • Current imaging diagnostic systems for HCC are valuable but require refinement.
  • Addressing limitations and inconsistencies is essential for seamless clinical integration and robust research.