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Updated: May 10, 2026
03:53
An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Huge sciatic neuroma presented 40 years after traumatic above knee amputation
K Daniilidis1, C M Stukenborg-Colsman, M Ettinger
1Department of Orthopaedic Surgery, Annastift Hannover Medical School Hannover, MHH, 30625 Hannover, Germany. Kiriakos.Daniilidis@gmx.de
Summary
Surgical revision of a stump neuroma provided complete pain relief for an above-knee amputee. This effective treatment allowed full weight-bearing mobilization and improved prosthetic use in a patient with chronic pain.
Area of Science:
- Orthopedic Surgery
- Neurology
- Rehabilitation Medicine
Background:
- Approximately 70,000 major/minor amputations are performed annually in Germany due to various conditions.
- Stump-related complications can lead to prosthetic incompatibility and patient immobility over time.
Observation:
- A 62-year-old patient experienced chronic, burning stump pain 40 years post-traumatic above-knee amputation.
- Previous consultations and prosthesis modifications offered only partial relief for the debilitating pain.
Findings:
- Clinical examination and MRI confirmed a stump neuroma of the sciatic nerve.
- Surgical resection of the neuroma and local flap graft correction resulted in complete postoperative pain relief.
Implications:
- Neurinoma should be considered in amputees presenting with chronic stump pain and associated immobility.
- Surgical intervention for stump neuromas can significantly improve patient quality of life and prosthetic function.
