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Updated: Aug 7, 2026

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Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers
Published on: October 29, 2021
Prosthesis receipt is associated with improved participation and pain interference following upper limb amputation
Bretta L Fylstra1, Kristin E Nalivaika1, Dwiesha L England1
1Hanger Institute for Clinical Research and Education, Austin, TX, USA.
Summary
Receiving a prosthesis after upper limb amputation (ULA) significantly improves social participation and reduces pain interference. This aids in resuming daily activities and enhances overall well-being for amputees.
Area of Science:
- Rehabilitation Medicine
- Prosthetics and Orthotics
- Pain Management
Background:
- Upper limb amputation (ULA) presents challenges in resuming daily activities.
- Prostheses can enhance physical function and well-being post-amputation.
- Understanding the impact of prosthesis receipt on social participation and pain is crucial for patient recovery.
Purpose of the Study:
- To investigate the relationship between prosthesis receipt and the Ability to Participate in Social Roles and Activities (APSRA).
- To examine the impact of prosthesis use on Pain Interference (PI) following ULA.
- To evaluate changes in APSRA and PI within twelve months of prosthesis receipt.
Main Methods:
- Retrospective cross-sectional review of outcomes from US private prosthetic clinics.
- Inclusion criteria: outcome data collected before and within 12 months after prosthesis receipt.
- Analysis accounted for confounders: age, hours worn, sex, amputation level, and time since amputation.
Main Results:
- Significant improvement in average APSRA scores from baseline (41.5±8.2) to follow-up (46.7±9.1, p<0.001).
- Significant reduction in average PI scores from baseline (58.5±8.5) to follow-up (54.9±9.3, p<0.001).
- These improvements remained significant after adjusting for potential confounding variables.
Conclusions:
- Prosthesis receipt positively impacts individuals' capacity for activity and social participation.
- Improved participation coincided with a decrease in pain interference.
- Findings support prosthesis use as a valuable intervention for enhancing outcomes after ULA.

