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Nuclear erythroid 2-related factor 2: a novel potential therapeutic target for liver fibrosis

Jing-Jing Yang1, Hui Tao, Cheng Huang

  • 1School of Pharmacy, Anhui Medical University, Hefei 230032, China.

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
|June 25, 2013
PubMed

Keywords:
APAPAREECMEGFERKExtracellular signal-regulated kinaseHCCHO-1HSCHepatic stellate cellITCKEAP1Liver fibrosisMAPKNASHNF-κBNOTCH 1Notch homolog 1Nrf2Nuclear erythroid 2-related factor 2Oxidative stressPCPPDGFPERKPI3KPKCPKR-like endoplasmic reticulum kinasePentachlorophenolPhosphoinositide 3-kinase inhibitorRNSROSTBARsTGF-β1acetaminophenantioxidant response elementepidermal growth factorextracellular matrixheme oxygenase-1hepatic stellate cellshepatocellular carcinomaisothiocyanateskelch-like ECH-associated protein 1mTORmammalian target of rapamycinmitogen-activated protein kinasenonalcoholic steatohepatitisnuclear erythroid 2-related factor 2nuclear factor-κBplatelet-derived growth factorprotein kinase Creactive nitrogen speciesreactive oxygen speciesthiobarbituric- acid-reactive substancestransforming growth factor-β1α-SMAα-smooth muscle actin

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