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Updated: May 10, 2026

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Picomolar detection of mercuric ions by means of gold-silver core-shell nanorods
Shouhui Chen1, Dingbin Liu, Zhihua Wang
1Department of Bio-Nano-Science and Engineering, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiaotong University, Shanghai 200240, China.
Abstract:
We report an ultrasensitive and selective probe for detection of mercuric ions using gold-silver core-shell nanorods as the substrate of surface-enhanced Raman scattering. The detection limit of this probe for mercuric ions can be as low as 1 pM. The efficiency of this probe in complex samples was evaluated by allowing detection of spiked mercuric ions in river water and fish samples.

