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Related Experiment Video

Updated: May 10, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

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Published on: October 20, 2016

Left ventricular twist in left ventricular noncompaction.

Ferande Peters1, Bijoy K Khandheria, Elena Libhaber

  • 1Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa.

European Heart Journal. Cardiovascular Imaging
|June 25, 2013
PubMed
Summary
This summary is machine-generated.

Left ventricular twist is reduced in patients with left ventricular noncompaction (LVNC). While rigid body rotation occurs in over half of LVNC patients, it does not worsen cardiac remodeling.

Keywords:
Left ventricular noncompactionRigid body rotationTwist

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Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Mechanics

Background:

  • Left ventricular (LV) twist is crucial for systolic function.
  • The impact of abnormal LV twist on cardiac remodeling in LVNC is not well understood.

Purpose of the Study:

  • To assess LV twist in patients with LVNC using speckle-tracking echocardiography.
  • To investigate the association between abnormal LV twist and adverse LV remodeling in LVNC.

Main Methods:

  • Prospective comparison of 60 LVNC patients and 59 controls.
  • Evaluation of LV twist, including net instantaneous twist and rigid body rotation (RBR).
  • Analysis of clinical, echocardiographic, and myocardial deformation parameters.

Main Results:

  • Diminished LV twist (apical, basal, and net) was observed in LVNC patients with normal rotation compared to controls.
  • Rigid body rotation (RBR) was present in 53.3% of LVNC patients.
  • LVNC patients with RBR showed worse NYHA functional status but similar remodeling indices and ejection fraction.

Conclusions:

  • LV twist is reduced in LVNC patients, even with normal rotation.
  • RBR in LVNC is common but not linked to increased adverse cardiac remodeling.