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Use of vitamin D supplements during infancy in an international feeding trial
Insights
Vitamin D supplement use in infancy varied significantly by region. European infants showed high usage, while Canadian infants had moderate use, and US/Australian infants had very low vitamin D supplementation rates.
Area of Science:
- Pediatric Nutrition
- Public Health
- Endocrinology
Background:
- Infant vitamin D supplementation is crucial for bone health and immune function.
- Geographical variations in vitamin D supplementation practices are not well-documented.
- Understanding supplementation patterns informs public health recommendations.
Purpose of the Study:
- To investigate the prevalence and patterns of vitamin D supplementation in infants across multiple countries.
- To identify factors associated with vitamin D supplement use in early infancy.
Main Methods:
- A longitudinal study design was employed.
- Data on vitamin D supplementation were collected using a validated food frequency questionnaire (FFQ).
- Information was gathered at 2 weeks and monthly up to 6 months of age in 2159 high-risk infants across Europe, USA, Canada, and Australia.
Main Results:
- Daily vitamin D supplementation exceeded 80% in Northern/Central Europe and 60% in Southern Europe.
- In Canada, 71% of exclusively breastfed infants received vitamin D at 6 months, compared to 44% of others.
- Less than 2% of infants in the USA and Australia received vitamin D supplements; higher gestational age, maternal age, and education correlated with increased use.
Conclusions:
- Vitamin D supplementation was common in European infants but less so in Canada, USA, and Australia.
- Significant geographical disparities in infant vitamin D supplementation exist.
- Maternal and infant factors influence vitamin D supplementation adherence.
Objective:
To examine the use of vitamin D supplements during infancy among the participants in an international infant feeding trial.
Design:
Longitudinal study.
Setting:
Information about vitamin D supplementation was collected through a validated FFQ at the age of 2 weeks and monthly between the ages of 1 month and 6 months.
Subjects:
Infants (n 2159) with a biological family member affected by type 1 diabetes and with increased human leucocyte antigen-conferred susceptibility to type 1 diabetes from twelve European countries, the USA, Canada and Australia.
Results:
Daily use of vitamin D supplements was common during the first 6 months of life in Northern and Central Europe (>80% of the infants), with somewhat lower rates observed in Southern Europe (> 60%). In Canada, vitamin D supplementation was more common among exclusively breast-fed than other infants (e.g., 71% v. 44% at 6 months of age). Less than 2% of infants in the U.S.A. and Australia received any vitamin D supplementation. Higher gestational age, older maternal age and longer maternal education were study-wide associated with greater use of vitamin D supplements.
Conclusions:
Most of the infants received vitamin D supplements during the first 6 months of life in the European countries, whereas in Canada only half and in the U.S.A. and Australia very few were given supplementation.
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