Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...
Biological Clocks and Seasonal Responses02:45

Biological Clocks and Seasonal Responses

The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response01:15

Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response

Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Chromatin Position Affects Gene Expression02:35

Chromatin Position Affects Gene Expression

Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences  access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area. 
Topologically Associated Domains (TADs)
The 3-dimensional positioning of chromatin in the nucleus influences the timing and level of...
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trends and risk factors of patient falls in Korean hospitals: A five-year national reporting data analysis.

PloS one·2026
Same author

Repression of ABA-responsive alternative splicing by an Arabidopsis SR protein relieves ABA inhibition of early plant growth.

The Plant cell·2026
Same author

Healthcare professionals' conceptualizations of palliative care and readiness for early integration: a cross‑sectional mixed‑methods survey in Finland.

BMC palliative care·2026
Same author

Limited Cross-Neutralization of Emerging SARS-CoV-2 BA.3.2.2 After LP.8.1-Updated Vaccination.

Journal of medical virology·2026
Same author

In vivo binding by <i>Arabidopsis</i> SPLICING FACTOR 1 shifts 3' splice-site choice, regulating circadian rhythms and immunity in plants.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Large-scale association study identifies lung cancer susceptibility copy number variants and their potential functional role in genetic instability.

medRxiv : the preprint server for health sciences·2026

Related Experiment Video

Updated: May 10, 2026

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
06:53

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Published on: November 11, 2016

The circadian clock goes genomic.

Dorothee Staiger, Jieun Shin, Mikael Johansson

    Genome Biology
    |June 26, 2013
    PubMed
    Summary
    This summary is machine-generated.

    Comparative genomics and large-scale plant biology studies have significantly improved our understanding of the plant circadian clock. This research explores the intricate timing system that governs plant life cycles and responses.

    More Related Videos

    Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
    10:38

    Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters

    Published on: September 27, 2012

    Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter
    07:42

    Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter

    Published on: September 17, 2016

    Related Experiment Videos

    Last Updated: May 10, 2026

    Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
    06:53

    Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

    Published on: November 11, 2016

    Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
    10:38

    Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters

    Published on: September 27, 2012

    Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter
    07:42

    Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter

    Published on: September 17, 2016

    Area of Science:

    • Plant Biology
    • Genomics
    • Chronobiology

    Background:

    • The plant circadian clock is a fundamental biological mechanism controlling daily rhythms.
    • Understanding its architecture and output processes is crucial for plant science.

    Purpose of the Study:

    • To advance the understanding of the endogenous timing system in plants.
    • To explore comparative genomics of circadian clock architecture.
    • To investigate clock-regulated output processes.

    Main Methods:

    • Large-scale biological data analysis across plant species.
    • Comparative genomic analyses.
    • Investigating clock-regulated outputs.

    Main Results:

    • Significant advancements in comprehending the plant circadian system.
    • Insights into the diversity of circadian clock architecture.
    • Detailed understanding of clock-regulated outputs.

    Conclusions:

    • Large-scale biology and comparative genomics are powerful tools for studying plant circadian clocks.
    • Our knowledge of plant endogenous timing systems has been greatly enhanced.