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A rat model for orthodontic translational expansive tooth movement
J C Danz1, M Dalstra, D D Bosshardt
1Department of Dentistry, Section of Periodontology, Aarhus University, Aarhus, Denmark; Department of Orthodontics and Dentofacial Orthopedics, School of Dental Medicine, University of Bern, Bern, Switzerland.
Orthodontics & Craniofacial Research
|June 26, 2013
Summary
This study developed an experimental rat model for translational expansive tooth movement, achieving symmetrical maxillary expansion. Findings highlight the importance of distinguishing between dental and skeletal movements in orthodontic research.
Area of Science:
- Biomedical Engineering
- Orthodontics
- Periodontology
Background:
- Developing reliable animal models is crucial for advancing orthodontic research.
- Translational expansive tooth movement requires precise experimental control and assessment.
Purpose of the Study:
- To develop and validate an experimental rat model for translational expansive tooth movement.
- To assess the efficacy of transpalatal β-titanium springs for maxillary expansion in rats.
Main Methods:
- Utilized Wistar rats with transpalatal β-titanium springs to induce buccal movement of molars.
- Investigated effects of different spring forces and preangulations on tooth movement.
- Assessed tooth movement and skeletal changes using microCT and histological analysis.
Main Results:
- Achieved expansive translational root movement equivalent to half a tooth width.
- Demonstrated symmetrical expansion in the maxilla of the P2 group.
- Found that skeletal widening accounted for one-third, and dental movement for two-thirds of the total root movement.
Conclusions:
- The developed rat model (P2 group) is suitable for further research on translational expansive tooth movement and its periodontal effects.
- Recommends separating the evaluation of skeletal and dental effects in orthodontic expansion models.
