Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 10, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

MALT lymphoma: forget surgery?

Wolfgang Fischbach1

  • 1Medizinische Klinik II und Klinik für Palliativmedizin, Klinikum Aschaffenburg, Akademisches Lehrkrankenhaus der Universität Würzburg, Aschaffenburg, Germany. wolfgang.fischbach@klinikum-aschaffenburg.de

Digestive Diseases (Basel, Switzerland)
|June 26, 2013
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Watch-and-Wait and surveillance in gastric MALT-lymphoma after exclusive Helicobacter pylori eradication under special consideration of patients' compliance].

Zeitschrift fur Gastroenterologie·2025
Same author

Correction: From modern pathogenetic insights and molecular understanding to new deescalating therapeutic strategies in gastric MALT-lymphoma.

Zeitschrift fur Gastroenterologie·2024
Same author

From modern pathogenetic insights and molecular understanding to new deescalating therapeutic strategies in gastric MALT-lymphoma.

Zeitschrift fur Gastroenterologie·2024
Same author

[Gastrointestinal mucosa-associated lymphoma].

Innere Medizin (Heidelberg, Germany)·2024
Same author

[Colorectal Cancer: Strategies for a better prevention and screening].

MMW Fortschritte der Medizin·2024
Same author

Zeitschrift fur Gastroenterologie·2024

Treatment for gastric MALT lymphoma begins with Helicobacter pylori eradication, achieving remission in 70-80% of patients. Non-responders or advanced stages may require radiation or chemotherapy.

Area of Science:

  • Gastroenterology
  • Oncology
  • Hematology

Background:

  • Gastric marginal zone B cell lymphoma of MALT (mucosa-associated lymphoid tissue) treatment is guided by established German and European consensus reports.
  • Helicobacter pylori (H. pylori) infection is a primary factor in gastric MALT lymphoma development.

Purpose of the Study:

  • To outline current standardized treatment strategies for gastric MALT lymphoma.
  • To discuss management approaches for non-responders and advanced stages of the disease.
  • To address the treatment of diffuse large B cell lymphoma (DLBCL) of the stomach.

Main Methods:

  • Review of German S3 guideline (2009) and European (EGILS) consensus report (2011).
  • Focus on H. pylori eradication as the first-line therapy for gastric MALT lymphoma.

More Related Videos

Murine Superficial Lymph Node Surgery
04:36

Murine Superficial Lymph Node Surgery

Published on: May 21, 2012

Related Experiment Videos

Last Updated: May 10, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Murine Superficial Lymph Node Surgery
04:36

Murine Superficial Lymph Node Surgery

Published on: May 21, 2012

  • Description of subsequent treatment modalities including radiation, chemotherapy, and watchful waiting.

    • Main Results:

    • Successful H. pylori eradication leads to complete remission in 70-80% of gastric MALT lymphoma patients.
    • Non-responders to eradication therapy are treated with radiation (stages I-II) or chemotherapy (stages III-IV).
    • Immunochemotherapy with rituximab and CHOP protocol is the standard for gastric DLBCL, offering good curative potential.

    Conclusions:

    • H. pylori eradication is the primary treatment for gastric MALT lymphoma.
    • Treatment selection for gastric MALT lymphoma depends on H. pylori status, lymphoma stage, and response to initial therapy.
    • Gastric DLBCL is managed with immunochemotherapy, with H. pylori eradication as a potential adjunctive measure.