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Related Experiment Video

Updated: Jun 24, 2025

Application of a Mouse Ligated Peyer’s Patch Intestinal Loop Assay to Evaluate Bacterial Uptake by M cells

Application of a Mouse Ligated Peyer’s Patch Intestinal Loop Assay to Evaluate Bacterial Uptake by M cells

Published on: December 17, 2011

[Gastrointestinal mucosa-associated lymphoma].

Wolfgang Fischbach^1,2, Andreas Neubauer³, Gabriele Reinartz⁴

¹Medizinische Klinik II und Klinik für Palliativmedizin, Klinikum Aschaffenburg-Alzenau, Akademisches Lehrkrankenhaus der Universität Würzburg, Aschaffenburg, Deutschland. wuk.fischbach@gmail.com.

Innere Medizin (Heidelberg, Germany)

|June 4, 2024

Summary

Helicobacter pylori eradication is the primary treatment for gastric MALT lymphoma, achieving remission in most cases. Advanced stages or treatment failures may require radiotherapy or immuno-chemotherapy.

Keywords:

Helicobacter pylori Mucosa-associated lymphoid tissue Mucosa-associated lymphoma/chemotherapy Mucosa-associated lymphoma/immunotherapy Mucosa-associated lymphoma/radiotherapy

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Last Updated: Jun 24, 2025

Application of a Mouse Ligated Peyer’s Patch Intestinal Loop Assay to Evaluate Bacterial Uptake by M cells

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Published on: December 17, 2011

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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

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Published on: March 30, 2018

Area of Science:

Gastroenterology
Oncology
Pathology

Context:

Mucosa-associated lymphomas of the gastrointestinal tract present diverse characteristics.
Accurate staging is crucial for effective treatment of these lymphomas.

Purpose:

To outline current therapeutic strategies for gastrointestinal MALT lymphomas.
To highlight the role of Helicobacter pylori in gastric MALT lymphoma.

Summary:

Gastric MALT lymphoma treatment centers on Helicobacter pylori eradication, with high remission rates.
Localized stages (I/II) respond well to radiotherapy if eradication fails.
Advanced stages (III/IV) are managed with immuno-chemotherapy; surgery is not indicated.
Intestinal and colorectal MALT lymphomas necessitate individualized treatment plans.

Impact:

Establishes Helicobacter pylori eradication as the standard of care for gastric MALT lymphoma.
Defines the roles of radiotherapy and immuno-chemotherapy based on disease stage.
Emphasizes a shift away from surgical intervention for gastric MALT lymphoma.