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Updated: May 10, 2026

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Transvaginal Mesh Insertion in the Ovine Model
Published on: July 27, 2017
Pathologic evaluation of explanted vaginal mesh: interdisciplinary experience from a referral center
Tovia M Smith1, Steven C Smith, John O Delancey
1Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Michigan Health System, Ann Arbor, MI, USA. toviasmith@gmail.com
Female Pelvic Medicine & Reconstructive Surgery
|June 26, 2013
Summary
Pathologic examination of explanted vaginal mesh is appropriate. Incomplete documentation of clinical history and mesh material hinders accurate gross examination and necessitates further histologic study.
Area of Science:
- Urogynecology
- Pathology
- Medical Device Analysis
Background:
- Vaginal mesh use has raised safety concerns, necessitating thorough evaluation of explanted devices.
- Pathologic examination plays a crucial role in understanding mesh complications and improving patient care.
Purpose of the Study:
- To review institutional experience with analytic processes and pathologic findings of explanted vaginal mesh.
- To identify areas for improvement in documentation and research related to vaginal mesh explants.
Main Methods:
- Retrospective review of gross and microscopic pathology reports and slides of explanted mesh specimens (January 2010-February 2012).
- Abstraction of clinical history, specimen details, and examination type from pathology records.
Main Results:
- 102 cases reviewed; 97% of explants contained tissue.
- Clinical history was frequently incomplete (24.5%), often leading to increased histopathologic examination.
- Mesh material (polypropylene) was rarely documented, and gross descriptions were sometimes inaccurate (e.g., "metallic").
Conclusions:
- Both gross and histopathologic examination are suitable for mesh explants.
- Incomplete documentation of clinical history and mesh material is common.
- Improved documentation is recommended to enhance pathologic examination and facilitate future research on mesh complications.
