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Published on: December 13, 2019
Evaluation of left ventricular systolic function with pulsed wave tissue Doppler in rheumatic mitral stenosis
Saadet Guven, Taner Sen1, Omac Tufekcioglu
1Department of Cardiology, Dumlupinar University Kutahya Evliya Celebi Education and Research Hospital, Turkey. medicineman_tr@hotmail.com.
Background:
Mitral stenosis (MS) is still the most common complication of acute rheumatic fever in Turkey. Rheumatic carditis affects not only cardiac valves but also myocardium. In this study, we aimed to evaluate the subclinical left ventricular (LV) systolic dysfunction and contraction of short and long axial circumferential and longitudinal fibers by pulsed wave tissue Doppler in rheumatic MS patients who have preserved LV systolic function in 2D echocardiography.
Methods:
Fifteen severe, 20 moderate rheumatic MS patients hospitalized for mitral balloon valvuloplasty, and 15 patients who had normal echocardiographic findings were included in the study. After routine conventional transthoracic echocardiographic examination, LV myocardial systolic velocities were evaluated with pulsed wave tissue Doppler in the short and long axis with simultaneous electrocardiographic monitoring.
Results:
Long axis first systolic velocity (SW1) of mild-moderate and severe MS was much lower than normal group (10.7 ± 2.3 in normal group vs. 7.9 ± 1.3 in mild-moderate MS group vs. 6.2 ± 1.4 in severe MS group, p < 0.001). Long axis Q-SW1 duration was longer in mild-moderate MS group (145 ± 32 in normal group vs. 199 ± 43 in mild-moderate MS group, p = 0.001). Short axis Q-SW2 duration was longer in normal group compared to mild-moderate and severe MS groups (298 ± 41 in normal group vs. 245 ± 37 in mild-moderate MS group vs. 234 ± 26 in severe MS group, p < 0.001). Significant correlation between mitral valve area and SW1, Q-SW1 was determined (p = 0.01).
Conclusions:
Even if LV functions are normal with conventional 2D echocardiography, subclinical systolic dysfunction exists in MS. Also, there is a dyssynchrony between contraction of longitudinal and circumferential myofibrils.
Insights
Subclinical systolic dysfunction is present in patients with mitral stenosis (MS), even with normal 2D echocardiography. Pulsed wave tissue Doppler reveals impaired myocardial fiber contraction and dyssynchrony in rheumatic MS.
Area of Science:
- Cardiology
- Echocardiography
- Rheumatic Heart Disease
Background:
- Mitral stenosis (MS) is a common complication of acute rheumatic fever in Turkey.
- Rheumatic carditis can affect cardiac valves and myocardium.
- This study investigates subclinical left ventricular (LV) dysfunction in rheumatic MS patients.
Purpose of the Study:
- To evaluate subclinical LV systolic dysfunction in rheumatic MS patients.
- To assess myocardial fiber contraction using pulsed wave tissue Doppler.
- To identify dysfunction in patients with preserved LV systolic function on 2D echocardiography.
Main Methods:
- Inclusion of 15 severe MS, 20 moderate MS, and 15 healthy control patients.
- Conventional transthoracic echocardiography followed by pulsed wave tissue Doppler analysis.
- Evaluation of LV myocardial systolic velocities in short and long axes with ECG monitoring.
Main Results:
- Long axis systolic velocity (SW1) was significantly lower in mild-moderate and severe MS groups compared to controls.
- Long axis Q-SW1 duration was prolonged in the mild-moderate MS group.
- Short axis Q-SW2 duration was shorter in MS groups compared to controls, indicating dyssynchrony.
Conclusions:
- Subclinical systolic dysfunction exists in MS patients, even with normal 2D echocardiography findings.
- There is evidence of dyssynchrony between longitudinal and circumferential myocardial fiber contraction in MS.
- Pulsed wave tissue Doppler is valuable for detecting early myocardial dysfunction in MS.
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