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Updated: May 10, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Published on: January 7, 2019
Universal tumor-reactive helper peptides from telomerase as new tools for anticancer vaccination
Magalie Dosset1, Charline Vauchy, Laurent Beziaud
1INSERM; Unité Mixte de Recherche 1098; Besançon, France ; Etablissement Français du Sang de Bourgogne Franche-Comté; UMR1098; Besançon, France ; Université de Franche-Comté; UMR1098; SFR IBCT; Besançon, France.
Abstract:
Accumulating evidence demonstrates the importance of CD4+ T cells in antitumor immune responses. Identifying promiscuous MHC class II-binding peptides derived from relevant tumor-associated antigens that specifically target CD4+ helper T cells in vivo represent a powerful approach to fully exploit these cells for anticancer immunotherapy.
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