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Related Concept Videos

Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
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Pneumonia II: Pathophysiology01:29

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Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
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Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

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Updated: May 10, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Do you really know precise radiologic-pathologic correlation of usual interstitial pneumonia?

Takeshi Johkoh1, Hiromotsu Sumikawa2, Junya Fukuoka3

  • 1Department of Radiology, Kinki Central Hospital of Mutual Aid Association of Public School Teachers, Itami, Japan.

European Journal of Radiology
|June 29, 2013
PubMed
Summary

This study explains the pathological basis of common and uncommon computed tomography (CT) findings in usual interstitial pneumonia (UIP). Radiologists play a key role in diagnosing UIP, especially honeycombing, as per guidelines.

Keywords:
CTHoneycombingPathologic correlationUsual interstitial pneumonia

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Last Updated: May 10, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Area of Science:

  • Pulmonary Medicine
  • Radiology
  • Pathology

Background:

  • Usual interstitial pneumonia (UIP) is the most frequent chronic interstitial lung disease.
  • Pathological understanding of CT findings in UIP remains incomplete.
  • Accurate diagnosis of UIP relies heavily on identifying honeycombing.

Purpose of the Study:

  • To correlate radiologic findings on CT scans with pathological backgrounds in UIP.
  • To elucidate the significance of common and uncommon CT features in UIP diagnosis.
  • To emphasize the crucial role of radiologists in UIP diagnosis.

Main Methods:

  • Review of CT imaging in patients with histopathologically confirmed UIP.
  • Correlation of specific CT findings with underlying lung pathology.
  • Analysis of common and uncommon imaging patterns.

Main Results:

  • Detailed description of characteristic and atypical CT manifestations of UIP.
  • Radiopathological correlation provided for key diagnostic features like honeycombing.
  • Insights into the spectrum of UIP imaging findings.

Conclusions:

  • Enhanced understanding of the pathological basis of CT findings in UIP is crucial.
  • Radiologists' expertise in interpreting CT scans is vital for accurate UIP diagnosis.
  • This review aids in improving diagnostic accuracy for UIP through radiologic-pathologic correlation.