Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Atypical fibroxanthoma, pleomorphic dermal sarcoma, and undifferentiated sarcoma: Updates on diagnosis, management, and surveillance.

Journal of the American Academy of Dermatologyยท2026
Same author

Automating Plasmid Construction for High-Throughput Heterologous Expression of Fungal Gene Clusters.

Methods in molecular biology (Clifton, N.J.)ยท2026
Same author

Development of a Core Outcome Domain Set for Facial Aging.

JAMA dermatologyยท2026
Same author

Reconstitution, Storage, and Infection Outcomes of Botulinum Toxin in Academic Dermatology: A National Survey.

Journal of the American Academy of Dermatologyยท2026
Same author

Management of Post-Procedure Eruptive Keratoacanthomas: A Retrospective Cohort Study.

Journal of the American Academy of Dermatologyยท2026
Same author

What US Medical Students Need to Learn About Clinical Practice Guidelines: A Qualitative Study of US Students and a Global Subset of Guidelines Developers.

Journal of clinical epidemiologyยท2026

Related Experiment Video

Updated: May 10, 2026

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy
07:12

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy

Published on: September 27, 2021

Floaters in Mohs micrographic surgery.

Murad Alam1, Anjali D Shah, Sana Ali

  • 1Department of Dermatology, Northwestern University, Chicago, Illinois; Department of Otolaryngology, Northwestern University, Chicago, Illinois; Department of Surgery, Northwestern University, Chicago, Illinois.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|July 2, 2013
PubMed
Summary
This summary is machine-generated.

Floaters, dislodged tumor tissue in Mohs micrographic surgery (MMS), are common and can obscure frozen sections. While causes like basal cell carcinomas are understood, management strategies for floaters lack consensus.

More Related Videos

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Related Experiment Videos

Last Updated: May 10, 2026

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy
07:12

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy

Published on: September 27, 2021

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Area of Science:

  • Dermatologic Surgery
  • Pathology
  • Oncology

Background:

  • Floaters, or dislodged tumor tissue fragments, frequently complicate Mohs micrographic surgery (MMS) by obscuring frozen sections and hindering accurate interpretation.
  • Understanding the incidence and origins of floaters is crucial for optimizing MMS procedures and diagnostic accuracy.

Framework:

  • A virtual consensus conference utilizing a 60-item questionnaire established expert agreement on floater causes.
  • Subsequent interviews with randomly selected Mohs surgeons validated these findings, ensuring robust data for analysis.

Implementation:

  • Analysis of 170,404 MMS cases across 230 surgeon-years revealed a 1.8% floater rate per tumor and 0.70% per tissue block.
  • Key contributing factors identified include not wiping blades between cuts, especially when separating tissue subunits, and the presence of basal cell carcinomas, ulcerated tumors, or tissue from initial surgical stages.

Implications:

  • Floaters are a significant, non-rare complication in MMS, impacting margin assessment and potentially requiring additional tissue processing.
  • While expert consensus exists on identifying and preventing floaters, standardized management protocols remain underdeveloped, highlighting a need for further research and guideline development.