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Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
Cranial Nerves: Overview and Anatomy01:19

Cranial Nerves: Overview and Anatomy

The cranial nerves are an important part of the complex network of nerves in the human body. These nerves emerge directly from the brain and are responsible for transmitting essential information between the brain and various parts of the head and neck. There are 12 pairs of cranial nerves, systematically numbered using Roman numerals from I to XII, beginning from the anterior and moving to the posterior of the brain. Each cranial nerve is uniquely identified by names that reflect its function...
Tooth Anatomy01:21

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Cranial Nerves: Types Part I01:14

Cranial Nerves: Types Part I

Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Muscles for Facial Expressions01:14

Muscles for Facial Expressions

The craniofacial muscles are a collection of approximately 20 thin skeletal muscles situated beneath the skin of the face and scalp. These muscles, primarily responsible for the vast array of human facial expressions, originate from the bones or fibrous structures of the skull and extend outwards to connect with the skin. While most skeletal muscles in the body are enveloped in thick fascia, facial muscles generally have a more delicate fascial covering, with the buccinator muscle being a...

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Related Experiment Video

Updated: May 10, 2026

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
07:39

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay

Published on: July 26, 2022

Orofacial pain: a primer.

Scott S De Rossi1

  • 1Department of Oral health and Diagnostic Sciences, College of Dental Medicine, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA. sderossi@gru.edu

Dental Clinics of North America
|July 2, 2013
PubMed
Summary
This summary is machine-generated.

Orofacial pain affects the head, face, and neck, impacting quality of life. Understanding its causes and management is crucial for clinicians.

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Last Updated: May 10, 2026

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
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Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice

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Area of Science:

  • Dentistry
  • Neurology
  • Pain Medicine

Background:

  • Orofacial pain is a prevalent condition with significant societal and quality-of-life implications.
  • Recent scientific advancements offer new insights into the etiology and mechanisms of orofacial pain.
  • Common conditions include temporomandibular disorders, cranial neuralgias, persistent idiopathic facial pain, headaches, and dental pain.

Purpose of the Study:

  • To provide a foundational review of orofacial pain epidemiology and neurophysiology.
  • To establish a basis for understanding the pathophysiology of diverse head and neck pain conditions.
  • To underscore the necessity of an evidence-based approach for managing orofacial pain.

Main Methods:

  • Review of current scientific literature on orofacial pain.
  • Synthesis of epidemiological data related to head, face, and neck pain.
  • Explanation of neurophysiological principles underlying pain perception.

Main Results:

  • Orofacial pain encompasses a wide range of conditions affecting soft and hard tissues.
  • Epidemiological data highlight the commonality and impact of these pain disorders.
  • Neurophysiological mechanisms are key to understanding pain generation and persistence.

Conclusions:

  • An evidence-based approach is essential for effective orofacial pain management.
  • This review serves as an introduction to detailed discussions on specific painful conditions.
  • Further understanding of pain mechanisms will improve clinical practice for orofacial pain.