Related Experiment Video
Updated: May 10, 2026

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model
Published on: September 27, 2024
Nanoparticle-DNA-polymer composites for hepatocellular carcinoma cell labeling, sensing, and magnetic resonance
Ken Cham-Fai Leung1, Siu-Fung Lee, Chi-Hin Wong
1Department of Chemistry, The Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong Special Administrative Region; Institute of Creativity, The Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong Special Administrative Region; Institute of Molecular Functional Materials, Areas of Excellence, University Grants Committee, Hong Kong Special Administrative Region.
Abstract:
This paper describes comparative studies and protocols in (1) self-assembling of ultrasmall superparamagnetic iron oxide nanoparticle (NP), circular plasmid DNA, and branched polyethylenimine (PEI) composites; (2) magnetofection; (3) gene delivery, (4) magnetic resonance imaging (MRI), and (5) cytotoxicity of the composites toward hepatocellular carcinoma HepG2 cells.

