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Small hepatic veins Budd-Chiari syndrome
Oliviero Riggio1, Chiara Marzano, Alessia Papa
1Gastroenterology, Department of Clinical Medicine, Sapienza University of Rome, Rome, Italy.
Journal of Thrombosis and Thrombolysis
|July 2, 2013
Summary
Budd-Chiari syndrome, a rare hepatic venous outflow obstruction, can affect small intrahepatic veins. Diagnosis may require liver biopsy when imaging large vessels appears normal.
Area of Science:
- Hepatology
- Vascular Medicine
- Diagnostic Imaging
Background:
- Budd-Chiari syndrome involves hepatic venous outflow obstruction.
- Rare forms affect small intrahepatic veins, challenging conventional imaging.
- Diagnosis requires differentiating from other causes of liver dysfunction.
Purpose of the Study:
- To highlight rare cases of small hepatic veins Budd-Chiari syndrome.
- To emphasize the diagnostic role of liver biopsy in specific presentations.
- To improve recognition of atypical Budd-Chiari syndrome.
Main Methods:
- Case report of two patients with small hepatic veins Budd-Chiari syndrome.
- Review of diagnostic imaging modalities (ultrasound, CT, MRI).
- Histopathological analysis of liver biopsy specimens.
Main Results:
- Imaging showed normal large hepatic veins in both cases.
- Liver biopsy confirmed obstruction in small intrahepatic veins.
- Clinical presentation varied, necessitating detailed investigation.
Conclusions:
- Small hepatic veins Budd-Chiari syndrome is an underdiagnosed entity.
- Liver biopsy is crucial for diagnosing cases with normal large vessel imaging.
- Increased awareness can improve early detection and management.
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