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Published on: August 15, 2025
Adenomatoid odontogenic tumour
Michael Prakasam1, Saba Tiwari, Mrinal Satpathy
1Department of Oral Surgery, Modern Dental College and Research Centre, Indore, Madhya Pradesh, India.
BMJ Case Reports
|July 2, 2013
Summary
Adenomatoid odontogenic tumour (AOT) is a rare, benign tumor affecting young women, often in the second decade. This case highlights an extrafollicular central variant of AOT, a slow-growing lesion adjacent to incisors.
Area of Science:
- Dentistry
- Oral Pathology
- Oncology
Background:
- Adenomatoid odontogenic tumour (AOT) is a rare, benign odontogenic neoplasm.
- It typically presents as a slow-growing lesion, predominantly in young individuals, with a female predilection.
- AOT is often considered a hamartoma due to its limited size and lack of recurrence.
Observation:
- This study details an extrafollicular central variant of AOT.
- This specific variant accounts for approximately 30% of AOT cases.
- The observed lesion was located adjacent to the incisor teeth.
Findings:
- The extrafollicular central variant of AOT demonstrates a slow and sustained growth pattern.
- Histopathological characteristics confirm its benign, non-invasive nature.
- The lesion's location adjacent to incisors is a key clinical observation.
Implications:
- Understanding AOT variants is crucial for accurate diagnosis and management.
- The benign nature of AOT suggests conservative treatment approaches.
- Further research into the specific behavior of the extrafollicular central variant may refine clinical guidelines.

