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Related Concept Videos

Free-falling Bodies: Introduction01:07

Free-falling Bodies: Introduction

All objects, neglecting air resistance, fall with the same acceleration towards the Earth's center due to the force exerted by the Earth's gravity. This experimentally determined fact is unexpected because we are so accustomed to the effects of air resistance and friction that we expect light objects to fall slower than heavier ones. People believed that a heavier object had a greater acceleration when falling until Galileo Galilei (1564–1642) proved otherwise. We now know this is not the case.
Altered States of Awareness01:06

Altered States of Awareness

Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
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Free-falling Bodies: Example01:05

Free-falling Bodies: Example

An object falling without any air resistance under the influence of gravitational force is said to be in free-fall. For free-falling bodies, the acceleration due to gravity is constant, irrespective of their mass. Free-fall is experienced not only by objects falling downward, but also by all objects whose motion is influenced by gravitational force alone. The dynamics of free-fall motion can be calculated using kinematic equations of motion, since free-fall acceleration is constant.
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Crossing Over01:30

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Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I, duplicated...
Crossing Over01:34

Crossing Over

Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
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Crossing over01:34

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Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
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A Time-lapse, Label-free, Quantitative Phase Imaging Study of Dormant and Active Human Cancer Cells
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Ghost cells: A journey in the dark….

Monica Mehendiratta1, Kundendu A Bishen, Karen Boaz

  • 1Department of Oral Pathology and Microbiology, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, India.

Dental Research Journal
|July 2, 2013
PubMed
Summary
This summary is machine-generated.

Ghost cells, also known as shadow or translucent cells, appear in various tumors. This review explores their controversial origins, nature, and significance across different neoplasms, suggesting a potential link between odontogenic and non-odontogenic tumors.

Keywords:
Craniopharygiomaghost cellnotch pathwayodontogenic cystodontogenic tumorpilomatricomashadow cellwnt pathway

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Area of Science:

  • Pathology
  • Oncology
  • Cell Biology

Background:

  • Ghost cells are eosinophilic cells observed in various neoplasms.
  • These cells are known by different names, such as 'ghost cells' in Calcifying cystic odontogenic tumor (CCOT) and 'shadow/translucent cells' in craniopharyngiomas and pilomatricomas.
  • Their origin, nature, and significance remain controversial due to incomplete knowledge.

Purpose of the Study:

  • To review the current understanding of ghost cells.
  • To explore the varying terminology and concepts surrounding these cells.
  • To investigate the potential link between odontogenic and non-odontogenic neoplasms exhibiting ghost cells.

Main Methods:

  • Literature review of scientific articles and case studies.
  • Comparative analysis of ghost cell characteristics in different tumor types.
  • Synthesis of existing knowledge on ghost cell biology and pathology.

Main Results:

  • Ghost cells are observed in both odontogenic (e.g., CCOT) and non-odontogenic tumors (e.g., craniopharyngiomas, pilomatricomas).
  • Despite varying nomenclature, these cells share descriptive similarities.
  • The presence of ghost cells across diverse neoplasms suggests a potential unifying biological mechanism or link.

Conclusions:

  • Ghost cells represent a conserved cellular phenomenon across different tumor types.
  • Further research is needed to elucidate the precise origin and significance of ghost cells.
  • Understanding ghost cells may provide insights into the pathogenesis of various neoplasms and potential therapeutic targets.