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Updated: May 10, 2026

Chitosan/Interfering RNA Nanoparticle Mediated Gene Silencing in Disease Vector Mosquito Larvae
Published on: March 25, 2015
Genetic control of Aedes mosquitoes
Luke Alphey1, Andrew McKemey, Derric Nimmo
1Oxitec Limited, 71 Milton Park, Oxford OX14 4RX, UK. uke.alphey@oxitec.com
Abstract:
Aedes mosquitoes include important vector species such as Aedes aegypti, the major vector of dengue. Genetic control methods are being developed for several of these species, stimulated by an urgent need owing to the poor effectiveness of current methods combined with an increase in chemical pesticide resistance. In this review we discuss the various genetic strategies that have been proposed, their present status, and future prospects. We focus particularly on those methods that are already being tested in the field, including RIDL and Wolbachia-based approaches.

