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Updated: May 10, 2026
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Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
Renal cell carcinoma presenting as mandibular metastasis
Hassan Ahmadnia1, Negar Mokhtari Amirmajdi, Ehsan Mansourian
1Mashhad University of Medical Sciences, Mashhad, Iran.
Summary
This case report details a rare instance of renal clear cell carcinoma (RCC) metastasizing to the mandible. Early detection of oral bone lesions is crucial for identifying potential advanced cancers like kidney cancer.
Area of Science:
- Oncology
- Urology
- Oral Pathology
Background:
- Renal clear cell carcinoma (RCC) can present with diverse clinical manifestations.
- Metastasis and paraneoplastic syndromes are uncommon presentations of RCC.
Observation:
- A 57-year-old patient presented with mandibular swelling, initially evaluated by a dentist.
- An incisional biopsy revealed metastatic renal clear cell carcinoma in the mandible.
Findings:
- Pathological examination confirmed metastatic clear cell carcinoma originating from the kidney.
- The patient subsequently underwent a right radical nephrectomy for the primary renal tumor.
Implications:
- Abnormal bone lesions in the oral cavity warrant thorough evaluation.
- The possibility of metastatic malignancy, including renal cell carcinoma, should be considered in oral bone lesions.
