[Incidence and susceptibility of Campylobacter jejuni in pediatric patients: involvement in bacteremia]

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Updated: May 10, 2026

Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
08:23

Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens

Published on: March 10, 2020

María José González-Abad1, Mercedes Alonso-Sanz

  • 1Sección de Microbiología, Servicio de Análisis Clínicos, Hospital Infantil Universitario Niño Jesús, Madrid, España. mjglezabad@yahoo.es

Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia
|July 3, 2013
PubMed

Insights

Campylobacter jejuni bacteremia is rare in children, primarily affecting immunocompromised individuals. High resistance to ciprofloxacin makes it unsuitable for empirical treatment, while erythromycin resistance remains low but requires monitoring.

Area of Science:

  • Pediatric Infectious Diseases
  • Microbiology
  • Antimicrobial Resistance

Background:

  • Invasive disease caused by Campylobacter species is infrequently reported.
  • Bloodstream infections are typically seen in immunocompromised patients or those with severe underlying conditions.

Purpose of the Study:

  • To determine the incidence of Campylobacter jejuni bacteremia in pediatric patients.
  • To assess the antimicrobial susceptibility of C. jejuni to erythromycin and ciprofloxacin.

Main Methods:

  • Prospective study conducted from April 2010 to June 2012 at Hospital Niño Jesús, Madrid.
  • Campylobacter isolates identified using standard culture methods.
  • Antimicrobial susceptibility testing performed via disk diffusion method.

Main Results:

  • 171 Campylobacter isolates from 154 pediatric patients; 66% identified as C. jejuni.
  • C. jejuni bacteremia occurred in 1.34% of all bloodstream infections, exclusively in immunocompromised children.
  • High resistance to ciprofloxacin (88%) and low resistance to erythromycin (5%) were observed.

Conclusions:

  • Campylobacter species are uncommon causes of bloodstream infections in children, predominantly affecting those with immune deficiencies.
  • Empirical use of fluoroquinolones for Campylobacter infections is not recommended due to high resistance rates.
  • Continued surveillance of erythromycin resistance in Campylobacter is advisable.
Abstract

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