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Related Concept Videos

Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Chronic Inflammation: Introduction

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Related Experiment Video

Updated: May 10, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

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Published on: December 15, 2011

[Giant rhinoscleroma].

K C Allah1, H Kossoko, V Assi Djè Bi Djè

  • 1Service de chirurgie plastique reconstructrice et esthétique, chirurgie de la main et brûlologie, CHU de Treichville, Abidjan 01, Côte-d'Ivoire. allahkchristophe@yahoo.fr

Revue De Stomatologie, De Chirurgie Maxillo-Faciale Et De Chirurgie Orale
|July 6, 2013
PubMed
Summary
This summary is machine-generated.

Rhinoscleroma, a chronic respiratory disease, can present as rare giant nasal tumors. Early antibiotic treatment is key to managing this infection and preventing recurrence.

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Published on: February 24, 2017

Area of Science:

  • Medicine
  • Pathology
  • Microbiology

Background:

  • Rhinoscleroma is a chronic granulomatous disease affecting the respiratory tract, typically originating in the nasal passages.
  • Giant tumor presentations of rhinoscleroma are uncommon, with the nasal mucosa being the most frequent initial site.

Observation:

  • A case report details a 35-year-old male with an extensive nasal rhinoscleroma presenting as a large tumor with associated nodules.
  • The tumor, initially a small intra-nasal growth, recurred after surgical removal, leading to complete nasal obstruction.
  • Histological and bacteriological examination confirmed rhinoscleroma, with trimethoprim-sulfamethoxazole proving effective against the infection.

Findings:

  • Rhinoscleroma, while often nasal, can manifest as rare extra-nasal giant tumors and involve the entire respiratory tract.
  • The condition is endemic in developing nations but also occurs sporadically in non-endemic regions, particularly among migrant populations.
  • Histological confirmation is crucial for diagnosis.

Implications:

  • Early and specific antibiotic therapy for rhinoscleroma is effective in treating the infection.
  • Prompt medical intervention can prevent surgical disfigurement, complications, and disease recurrence.